4,7-Dichloro-6-nitroquinazoline → HCID 18967569, 화합물

HRID 399495

반응식

HRID 399495 반응식
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([Cl:15])=[C:9]([N+:12]([O-:14])=[O:13])[CH:10]=2)[N:5]=[CH:4][N:3]=1.[N:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[CH2:22][O:23][C:24]1[C:25]([CH3:31])=[CH:26][C:27]([NH2:30])=[CH:28][CH:29]=1>>[Cl:15][C:8]1[CH:7]=[C:6]2[C:11]([C:2]([NH:30][C:27]3[CH:28]=[CH:29][C:24]([O:23][CH2:22][C:17]4[CH:18]=[CH:19][CH:20]=[CH:21][N:16]=4)=[C:25]([CH3:31])[CH:26]=3)=[N:3][CH:4]=[N:5]2)=[CH:10][C:9]=1[N+:12]([O-:14])=[O:13]

참가 물질

3

반응물 2

HCID 104904554,7-Dichloro-6-nitroquinazolineHCID 234382883-Methyl-4-(pyridin-2-ylmethoxy)aniline

생성물 1

HCID 18967569HCID 18967569, 화합물수율 81%

실험 절차

Using an analogous procedure to that described in Example 1, 4,7-dichloro-6-nitroquinazoline was reacted with 5-amino-2-tolyl 2-pyridylmethyl ether to give 7-chloro-4-[3-methyl-4-(2-pyridylmethoxy)anilino]-6-nitroquinazoline in 81% yield.

출처 및 근거

ORD 기록
ord-a2a4ef68da1048fba24fa83088329ecc
출처 데이터셋
uspto-grants-1998_10
특허 번호
US05821246

연결된 노트

불러오는 중…