Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-(4-Aminophenyl)propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2-Propenoic acid, 3-(4-nitrophenyl)- | HCID 70156 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-(4-Aminophenyl)propionic acid | HCID 75451 | — |
반응 단계
15 g of palladium on carbon (10% and 30 ml of water are added to a mixture of 155 g of 4-nitrocinnamic acid in 1 l of methanol, and hydrogenation is carried out at room temperature under 3 bar until no further hydrogen is taken up, after about 2 hours. After filtration and evaporation of the solvent in a rotary evaporator, residual water is removed by twice adding 300 ml portions of toluene and distilling off the solvent in a rotary evaporator.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05821240 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-080107e432b24871a28213b866e90934 |
| 출처 메모 | uspto-grants-1998_10 |