Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → 1-Benzyl-3-(3-chlorophenyl)-1-(cyanoacetyl)urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Cyanoacetic acid | HCID 9740 | — |
| 반응물 | 1-Benzyl-3-(3-chlorophenyl)urea | HCID 581390 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 1-Benzyl-3-(3-chlorophenyl)-1-(cyanoacetyl)urea | HCID 2822854 | — |
반응 단계
A mixture of 1-benzyl-3-(3-chlorophenyl)urea (44.78 g) and cyanoacetic acid (16.11 g) was ground together and then acetic anhydride (48 ml) added. The resulting mixture was heated and stirred at 75°-80° C. for 16 h. It was then allowed to cool, diluted with ether and the product filtered off and washed with ether. This was then recrystallised from toluene with a hot filtration. Yield=20.15 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05821366 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-14d924b3ea464728bb4f78179e52d8d6 |
| 출처 메모 | uspto-grants-1998_10 |