Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-(3-Chloro-2-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1-Chloro-3-isothiocyanato-2-methylbenzene | HCID 140504 | — |
| 반응물 | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-(3-Chloro-2-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one | HCID 18968212 | 83.3% |
반응 단계
The title compound was prepared by the procedure described in Example 1 using 13.2 g of 3-chloro-2-methylphenyl-isothiocyanate, 11.0 g of sarcosine ethyl ester hydrochloride, 25 g of triethyl amine, and 300 mL of chloroform. Crystallization from diethyl ether afforded the title compound (15.2 g) as a tan solid, m.p. 122°-124° C. Anal. Calcd. for C11H11Cl N2O S: C, 51.87; H, 4.35; N,11.00. Found: C, 51.96; H, 4.21; N, 11.05. Mass spectrum (EI, M.+) m/z 254/256.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05821372 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-58317836117e413f82d1d06fa2f3cd8b |
| 출처 메모 | uspto-grants-1998_10 |