Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(+-)-Pantolactone → Keto-pantoyllactone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (+-)-Pantolactone | HCID 989 | — |
| 반응물 | Trichloroisocyanuric Acid | HCID 6909 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 촉매 | Tempo | HCID 2724126 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Keto-pantoyllactone | HCID 39 | 89.4% |
반응 단계
2.5 g (19.2 mmol) of pantolactone were reacted with 1.8 g (7.7 mmol) of trichloroisocyanuric acid in the presence of 30 mg (0.12 mmol) of TEMPO derivative C and 1.65g (20.1 mmol) of sodium acetate analogously to Example 14. In contrast to Example 14, ethyl acetate (20 ml) was used as the solvent. The reaction had finished after 2 hours. After recrystallization of the crude product there were obtained 2.2 g (89%) of ketopantolactone, m.p. 68°-69° C., GC content: 100% (area percent).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05821374 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-eabf6f8f96b0446daa31797acac3cb72 |
| 출처 메모 | uspto-grants-1998_10 |