HCID 18945167, 화합물 → Methyl 3-formyl-5-(1H-pyrrol-1-yl)benzoate
반응식
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([N:13]2[CH:17]=[CH:16][CH:15]=[CH:14]2)[CH:12]=1)[C:6]([O:8][CH3:9])=[O:7]>ClCCl.[O-2].[O-2].[Mn+4]>[CH:2]([C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([N:13]2[CH:17]=[CH:16][CH:15]=[CH:14]2)[CH:12]=1)[C:6]([O:8][CH3:9])=[O:7])=[O:1]참가 물질
4
실험 절차
A mixture of methyl 3-hydroxymethyl-5-(pyrrol-1-yl)benzoate (20.0 g) and manganese dioxide (100.0 g) in dichloromethane (0.5 l) was stirred for 22 hours at room temperature. The manganese dioxide was filtered off and the filtrate was evaporated in vacuo. The residue was pulverized from diisopropyl ether and petroleum ether to give methyl 3-formyl-5-(pyrrol-1-yl)benzoate (17.6 g).
후처리
- filtrationThe manganese dioxide was filtered off
- customthe filtrate was evaporated in vacuo
출처 및 근거
- ORD 기록
- ord-5f260cc589b34e5eab58c04327dab822
- 출처 데이터셋
- uspto-grants-1998_10
- 특허 번호
- US05824691
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