참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 3,4,5-Trimethoxyphenylacetic acid | HCID 70372 | — |
| 촉매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-(3,4,5-trimethoxyphenyl)acetyl Chloride | HCID 11032124 | — |
반응 단계
Combine 3,4,5-trimethoxy-phenyl-acetic acid (2.26 g, 10 mmol) and dichloromethane (50 mL). Cool to -5° C. using a ice-salt bath. Add 2 drops of dimethylformamide followed by dropwise addition of oxalyl chloride (1.74 mL, 20 mmol). after 1 hour, warm the reaction mixture to ambient temperature. After 2 hours, evaporate the reaction mixture in vacuo to give the title compound as a liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05824690 |
|---|
| 출처 데이터셋 | uspto-grants-1998_10 |
|---|
| ORD ID | ord-1a265be0a8704ec68c71929a1a4730bb |
|---|
| 출처 메모 | uspto-grants-1998_10 |
|---|
