Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pravastatin Diol Lactone Di-(tert-butyldimethylsilyl) Ether → HCID 22856159, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pravastatin Diol Lactone Di-(tert-butyldimethylsilyl) Ether | HCID 14600906 | — |
| 반응물 | 2-Allyl-2-ethyl-4-pentenoyl chloride | HCID 18943933 | — |
| 생성물 | HCID 22856159 | HCID 22856159 | 77.5% |
반응 단계
A procedure similar to that described in Example 6, above, was followed, but using 1.65 g (3.0 mmol) of (4R,6R)-6-{2-[(1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above] and 2.80 g (15.0 mmol) of 2-allyl-2-ethyl-4-pentenoyl chloride, to provide 1.63 g of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05827855 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-f2547d94d05743ba8aa521bc86e38fda |
| 출처 메모 | uspto-grants-1998_10 |