Dimethylformamide → 4-(Chlorosulphonyl)benzoyl chloride

HRID 400521노트

반응식

HRID 400521 반응식
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[Cl:7][S:8]([C:11]1[CH:19]=[CH:18]C(C(O)=O)=[CH:13][CH:12]=1)(=[O:10])=[O:9].CN(C)C=O>ClCCl>[Cl:7][S:8]([C:11]1[CH:19]=[CH:18][C:1]([C:2]([Cl:4])=[O:3])=[CH:13][CH:12]=1)(=[O:10])=[O:9]

참가 물질

5

반응물 3

HCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 823854-(Chlorosulfonyl)benzoic acid

생성물 1

HCID 820244-(Chlorosulphonyl)benzoyl chloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Oxalyl chloride (2.2 mL) was added to a mixture of 4-(chlorosulfonyl)benzoic acid (0.662 g, 3.0 mmol) in anhydrous dichloromethane (25 mL) followed by one small drop of N,N-dimethylformamide. The mixture was stirred at room temperature overnight. Then the mixture was then concentrated to provide 4-(chlorosulfonyl)benzoyl chloride which was used without additional purification.

후처리

  1. concentrationThen the mixture was then concentrated

출처 및 근거

ORD 기록
ord-20593f4ad6564e18add7653c732f413a
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08741899B2

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