Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(-)-3-Hydroxytetrahydrofuran → HCID 86683314, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (-)-3-Hydroxytetrahydrofuran | HCID 641512 | — |
| 반응물 | 5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine | HCID 71558205 | — |
| 반응물 | HCID 178441789 | HCID 178441789 | — |
| 생성물 | HCID 86683314 | HCID 86683314 | — |
반응 단계
In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 61), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and (R)-tetrahydrofuran-3-ol and isolated as colorless gum. MS (m/e): 353.3 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08741906B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-00f85542af9c469b80734d6a43992148 |
| 출처 메모 | uspto-grants-2014_06 |