Iodocyclopentane → 6-(Cyclopentyloxy)-2-isopropyl-1-(pyridin-2-ylmethyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-indole-3-carboxamide

HRID 40134

반응식

HRID 40134 반응식
[OH:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:21]([NH:23][CH2:24][C:25]3[CH:26]=[N:27][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:29][CH:30]=3)=[O:22])=[C:7]([CH:18]([CH3:20])[CH3:19])[N:8]2[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)=[CH:4][CH:3]=1.[CH:35]1(I)[CH2:39][CH2:38][CH2:37][CH2:36]1>>[CH:35]1([O:1][C:2]2[CH:10]=[C:9]3[C:5]([C:6]([C:21]([NH:23][CH2:24][C:25]4[CH:26]=[N:27][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:29][CH:30]=4)=[O:22])=[C:7]([CH:18]([CH3:19])[CH3:20])[N:8]3[CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=3)=[CH:4][CH:3]=2)[CH2:39][CH2:38][CH2:37][CH2:36]1

참가 물질

3

반응물 2

HCID 73784IodocyclopentaneHCID 59762291HCID 59762291, 화합물2회

생성물 1

HCID 597623236-(Cyclopentyloxy)-2-isopropyl-1-(pyridin-2-ylmethyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-indole-3-carboxamide

실험 절차

The title compound was prepared from 6-hydroxy-2-isopropyl-1-(pyridin-2-ylmethyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-indole-3-carboxamide (Compound 141) and cyclopentyl iodide by General Procedure N.

출처 및 근거

ORD 기록
ord-3e1a967ccfb44c01b6c2f798819560ee
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08524917B2

연결된 노트

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