Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methoxy-3-nitropyridine → 3-Amino-2-methoxypyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methoxy-3-nitropyridine | HCID 253219 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-Amino-2-methoxypyridine | HCID 2737488 | 87% |
반응 단계
A solution of 2-methoxy-3-nitro-pyridine (70. g, 0.45 mol) in methanol (700 mL) containing palladium on carbon (7 g, 10%) was stirred under an atmosphere of hydrogen for 15 hours. The catalyst was filtered and washed with methanol. The filtrate was evaporated to dryness to give crude 2-methoxy-pyridin-3-ylamine (48 g, 0.39 mol, 87%), which was used directly in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08741939B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-a4a258994c364f5d8376e8f8bf129688 |
| 출처 메모 | uspto-grants-2014_06 |