Ethyl 2-thiopheneglyoxylate → HCID 67289955, 화합물

HRID 403429노트

반응식

HRID 403429 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([NH2:10])[C:5]([NH2:9])=[CH:6][C:7]=1[Cl:8].O=[C:12]([C:18]1[S:19][CH:20]=[CH:21][CH:22]=1)[C:13](OCC)=[O:14]>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:6][C:7]=1[Cl:8])[NH:9][C:13](=[O:14])[C:12]([C:18]1[S:19][CH:20]=[CH:21][CH:22]=1)=[N:10]2

참가 물질

4

반응물 2

HCID 77693Ethyl 2-thiopheneglyoxylateHCID 792974,5-Dichloro-1,2-phenylenediamine

생성물 1

HCID 67289955HCID 67289955, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
70 °C

실험 절차

A mixture of 4,5-dichlorobenzene-1,2-diamine (1.0 g, 5.65 mmol), ethyl 2-oxo-2-(thiophen-2-yl)acetate (1.056 g, 5.73 mmol) and ethanol (8 ml) was stirred at 70° C. for 11 h, cooled to room temperature, filtered and washed with cold ethanol. The collected pale yellow solid was dried further (1.07 g) and used directly in next step.

후처리

  1. temperaturecooled to room temperature
  2. filtrationfiltered
  3. washwashed with cold ethanol
  4. customThe collected pale yellow solid was dried further (1.07 g)

출처 및 근거

ORD 기록
ord-e2e509857fd348abbb23af2cdb1c66cc
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08748374B2

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