Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Difluoro-5-isocyanatobenzene → (S)-Methyl-2-(6-(4-(3-(3,5-difluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Difluoro-5-isocyanatobenzene | HCID 2779282 | — |
| 반응물 | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| 생성물 | (S)-Methyl-2-(6-(4-(3-(3,5-difluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 67305419 | — |
반응 단계
The compound of example 29 was prepared analogous to compound of example 7 by reaction of compound of example 6 with 3,5-difluorophenyl isocyanate. The compound of example 29 was used directly without isolation for the preparation of compound of example 30.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08748426B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-847d86da92de4549beb7c0c35ce255b2 |
| 출처 메모 | uspto-grants-2014_06 |