(S)-2-(6-(4-(3-(4-Fluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid → (S)-2-(6-(4-(3-(3,4-Difluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid

참여 물질

역할	이름	HCID	투입량
반응물	(S)-2-(6-(4-(3-(4-Fluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid	HCID 53303121	—
반응물	(S)-Methyl 2-(6-(4-(3-(3,4-difluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate	HCID 123749611	—
생성물	(S)-2-(6-(4-(3-(3,4-Difluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid	HCID 67306733	96%

The compound of example 32 was prepared analogous to compound of example 8 by hydrolysis of compound of example 31.