Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Difluorobenzoyl chloride → (S)-Methyl 2-(6-(4-(2,4-difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Difluorobenzoyl chloride | HCID 588081 | — |
| 반응물 | (S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123625862 | — |
| 반응물 | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| 생성물 | (S)-Methyl 2-(6-(4-(2,4-difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53303632 | — |
반응 단계
The compound of example 109 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 2,4-difluorobenzoyl chloride. The compound of example 109 was used directly without isolation for the preparation of compound of example 110.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08748426B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-b873271d7a844adf96282dbb7001b31d |
| 출처 메모 | uspto-grants-2014_06 |