Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluoro-3-(trifluoromethyl)benzoyl Chloride → (S)-Methyl 2-(6-(4-(4-fluoro-3-(trifluoromethyl)benzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluoro-3-(trifluoromethyl)benzoyl Chloride | HCID 144253 | — |
| 반응물 | (S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123625862 | — |
| 반응물 | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| 생성물 | (S)-Methyl 2-(6-(4-(4-fluoro-3-(trifluoromethyl)benzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731496 | 74% |
반응 단계
The compound of example 205 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 4-fluoro-3-trifluoromethyl benzoyl chloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08748426B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-88990ebf87fc49c7839a253032aa919f |
| 출처 메모 | uspto-grants-2014_06 |