4-(Trifluoromethyl)benzoyl bromide → HCID 131731525, 화합물
반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]3[C:14](=[CH:15][CH:16]=2)[C:13](=[O:17])[N:12]([C@@H:18]([CH:23]([CH3:25])[CH3:24])[C:19]([O:21][CH3:22])=[O:20])[CH2:11]3)=[CH:4][CH:3]=1.[F:26][C:27]([F:38])([F:37])[C:28]1[CH:36]=[CH:35][C:31]([C:32](Br)=[O:33])=[CH:30][CH:29]=1>>[CH3:24][CH:23]([CH3:25])[C@H:18]([N:12]1[CH2:11][C:10]2[C:14](=[CH:15][CH:16]=[C:8]([C:5]3[CH:6]=[CH:7][C:2]([NH:1][C:32](=[O:33])[C:31]4[CH:35]=[CH:36][C:28]([C:27]([F:26])([F:37])[F:38])=[CH:29][CH:30]=4)=[CH:3][CH:4]=3)[CH:9]=2)[C:13]1=[O:17])[C:19]([O:21][CH3:22])=[O:20]참가 물질
3
실험 절차
The compound of example 308 was prepared analogous to compound of example 304 by reaction of compound of example 223 with 4-trifluoromethyl benzoyl bromide. The compound of example 308 was used directly without isolation, for the preparation of compound of example 309.
출처 및 근거
- ORD 기록
- ord-58f1daedb01a4f959d903f50e2c3aece
- 출처 데이터셋
- uspto-grants-2014_06
- 특허 번호