Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Difluorophenyl isocyanate → (S)-Methyl 2-(6-(5-(3-(3,4-difluorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Difluorophenyl isocyanate | HCID 2734708 | — |
| 반응물 | (S)-Methyl 2-(6-(5-aminopyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731548 | — |
| 반응물 | (S)-Methyl 2-(6-(5-(3-(2-chlorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731549 | — |
| 생성물 | (S)-Methyl 2-(6-(5-(3-(3,4-difluorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 67323403 | 89% |
반응 단계
The compound of example 399 was prepared analogous to the compound of example 393 by reaction of the compound of example 392 with 3,4-difluoro phenyl isocyanate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08748426B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-08db04e440144962bbd0bd3e47b5bf16 |
| 출처 메모 | uspto-grants-2014_06 |