(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → 1-(1-Oxo-6-(4-(4-(trifluoromethoxy)benzamido)phenyl)isoindolin-2-yl)cyclopentane carboxylic acid
반응식
C(NC1C=CC(C2C=C3C(CN([C@@H](C(C)C)C(O)=O)C3=O)=CC=2)=CC=1)(=O)C1C=CC=CC=1.[O:33]=[C:34]1[C:42]2[C:37](=[CH:38][CH:39]=[C:40]([C:43]3[CH:48]=[CH:47][C:46]([NH:49][C:50](=[O:62])[C:51]4[CH:56]=[CH:55][C:54]([O:57][C:58]([F:61])([F:60])[F:59])=[CH:53][CH:52]=4)=[CH:45][CH:44]=3)[CH:41]=2)[CH2:36][N:35]1[C:63]1([C:68]([O:70]C)=[O:69])[CH2:67][CH2:66][CH2:65][CH2:64]1>>[O:33]=[C:34]1[C:42]2[C:37](=[CH:38][CH:39]=[C:40]([C:43]3[CH:48]=[CH:47][C:46]([NH:49][C:50](=[O:62])[C:51]4[CH:52]=[CH:53][C:54]([O:57][C:58]([F:60])([F:59])[F:61])=[CH:55][CH:56]=4)=[CH:45][CH:44]=3)[CH:41]=2)[CH2:36][N:35]1[C:63]1([C:68]([OH:70])=[O:69])[CH2:67][CH2:66][CH2:65][CH2:64]1참가 물질
3
반응물 2
생성물 1
실험 절차
The compound of example 535 was prepared analogous to compound of example 98 by hydrolysis of compound of example 534.