Methyl 3-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclohexanecarboxylate → HCID 67315555, 화합물

HRID 404056

반응식

HRID 404056 반응식
NC1C=CC(C2C=C3C(CN([C@@H](C(C)C)C(OC)=O)C3=O)=CC=2)=CC=1.[N+:26]([C:29]1[CH:34]=[CH:33][C:32]([C:35]2[CH:43]=[C:42]3[C:38]([CH2:39][N:40]([CH:45]4[CH2:50][CH2:49][CH2:48][CH:47]([C:51]([O:53][CH3:54])=[O:52])[CH2:46]4)[C:41]3=[O:44])=[CH:37][CH:36]=2)=[CH:31][CH:30]=1)([O-])=O>>[NH2:26][C:29]1[CH:30]=[CH:31][C:32]([C:35]2[CH:43]=[C:42]3[C:38]([CH2:39][N:40]([CH:45]4[CH2:50][CH2:49][CH2:48][CH:47]([C:51]([O:53][CH3:54])=[O:52])[CH2:46]4)[C:41]3=[O:44])=[CH:37][CH:36]=2)=[CH:33][CH:34]=1

참가 물질

3

반응물 2

HCID 67312960Methyl 3-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclohexanecarboxylateHCID 131731441(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate

생성물 1

HCID 67315555HCID 67315555, 화합물수율 72%

실험 절차

The compound of example 543 was prepared analogous to the compound of example 6 by reduction of the compound of example 542.

출처 및 근거

ORD 기록
ord-79d7fd5110df4f12ababb2952411bfcf
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08748426B2

연결된 노트

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