Calcium Carbonate → L-Rhamnitol

HRID 40456

반응식

HRID 40456 반응식
[O:1]=[CH:2][C@@H:3]([C@@H:5]([C@H:7]([C@H:9]([CH3:11])[OH:10])[OH:8])[OH:6])[OH:4].C(=O)([O-])[O-].[Ca+2].[H][H]>O>[CH2:2]([OH:1])[C@@H:3]([C@@H:5]([C@H:7]([C@H:9]([CH3:11])[OH:10])[OH:8])[OH:6])[OH:4]

참가 물질

5

반응물 3

HCID 10112Calcium CarbonateHCID 19233(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal2회HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 445052L-Rhamnitol

시약·촉매·용매 1

HCID 962Water용매

실험 절차

24 g of Raney-nickel obtained by the method described above was added to 300 g of an aqueous solution containing 100 g of 6-deoxy L-mannose in a 1-L glass autoclave with an agitator and a thermometer, to which water was added to a final reaction volume of 600 g. So as to adjust the reaction mixture to pH 7, then, calcium carbonate was added. Reaction was progressed while the temperature was retained at 50° C.; the hydrogen pressure was retained at 12 kg/cm2 (gauge pressure); the agitation speed was retained at 700 rpm. The reaction mixture was analyzed by HPLC. Consequently, 6-deoxy L-mannose was decreased to 1% in the 8-hour reaction, to produce 6-deoxy L-mannitol.

후처리

  1. customreaction volume of 600 g
  2. customReaction
  3. customwas retained at 50° C.

출처 및 근거

ORD 기록
ord-c8e3dfd703da496dbe1b8ec4c2014a7d
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08530222B2

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