6-Bromoisoquinolin-1(2H)-one → 6-Bromo-7-chloro-1,2-dihydroisoquinolin-1-one

HRID 404725노트

반응식

HRID 404725 반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[NH:7][CH:6]=[CH:5]2.BrC1C=C2C(=CC=1[Cl:24])C(Cl)=NC=C2>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[Cl:24])[C:8](=[O:12])[NH:7][CH:6]=[CH:5]2

참가 물질

3

반응물 2

HCID 158851826-Bromoisoquinolin-1(2H)-oneHCID 592262696-Bromo-1,7-dichloroisoquinoline

생성물 1

HCID 592262786-Bromo-7-chloro-1,2-dihydroisoquinolin-1-one

실험 절차

The title compound was prepared by the method, described for 6-Bromo-2H-isoquinolin-1-one (6), starting from 6-Bromo-1,7-dichloro-isoquinoline (11). Rt=1.26 min (Method C). Detected mass: 258.2/260.2 (M+H+).

출처 및 근거

ORD 기록
ord-9000d80a49c0411a8e42c8a3d03008ac
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08748614B2

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