Ammonium Hydroxide → HCID 86605522, 화합물

HRID 404999노트

반응식

HRID 404999 반응식
[OH-].[NH4+:2].[N:3]([CH2:6][CH2:7][CH2:8][S:9](Cl)(=[O:11])=[O:10])=[N+:4]=[N-:5]>C(O)C>[N:3]([CH2:6][CH2:7][CH2:8][S:9]([NH2:2])(=[O:11])=[O:10])=[N+:4]=[N-:5]

참가 물질

4

반응물 2

HCID 14923Ammonium HydroxideHCID 538209503-Azidopropane-1-sulfonyl chloride

생성물 1

HCID 86605522HCID 86605522, 화합물수율 86%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Ammonium hydroxide (28%) (10 mL) was added to a solution of 3-azido-1-propanesulfonyl chloride (˜2.29 g, 12.53 mmol; obtained in step 2) in ethanol (10 mL). The reaction mixture was stirred at room temperature for 3 h then concentrated. The residual material was passed through a short silica gel column using hexanes:ethyl acetate as eluent to isolate 3-azido-1-propanesulfonamide (1.5 g, 86%).

후처리

  1. concentrationthen concentrated

출처 및 근거

ORD 기록
ord-44f2ef1886bf4c5a910a7febca11a14d
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08748656B2

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