4-Bromo-3-methylaniline → 2',6'-Dichlorobiphenyl-4-ylamine
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1B(O)O.Br[C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][C:14]=1C.ClC1C=CC(B(O)O)=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][CH:14]=1참가 물질
4
반응 조건
- 온도
- 90 °C
실험 절차
The title compound was prepared as described in Example 76, STEP B, but heating at 90° C. for 14 hrs, substituting 4-iodoaniline and 2,6-dichlorophenylboronic acid for 4-bromo-3-methylaniline and 4-chlorophenylboronic acid.
출처 및 근거
- ORD 기록
- ord-e9b43b5023cb4e1780cf36bbeaf1420d
- 출처 데이터셋
- uspto-grants-2014_06
- 특허 번호
- US08748624B2
반응 노트
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