4-Bromo-3-chloroaniline → HCID 86674296, 화합물

HRID 405266

반응식

HRID 405266 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1I)[NH2:5].[Cl:10][C:11]1[CH:16]=[C:15]([O:17][CH3:18])[CH:14]=[CH:13][C:12]=1B(O)O.BrC1C=CC(N)=CC=1Cl.FC(F)(F)C1C=CC(B(O)O)=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH2:5])[CH:6]=[CH:7][C:8]=1[C:12]1[CH:13]=[CH:14][C:15]([O:17][CH3:18])=[CH:16][C:11]=1[Cl:10]

참가 물질

5

반응물 4

HCID 888884-Bromo-3-chloroanilineHCID 2829263-Chloro-4-iodoanilineHCID 27343894-(Trifluoromethyl)phenylboronic acidHCID 27733302-Chloro-4-methoxybenzeneboronic acid

생성물 1

HCID 86674296HCID 86674296, 화합물

실험 절차

The title compound was prepared as described in Example 159 substituting 3-chloro-4-iodoaniline and (2-chloro-4-methoxyphenyl)boronic acid for 4-bromo-3-chloroaniline and (4-(trifluoromethyl)phenyl)boronic acid, respectively.

출처 및 근거

ORD 기록
ord-25b002f29551486d97044d2b393f65ec
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08748624B2

연결된 노트

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