참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Sec-Butylamine | HCID 24874 | — |
| 반응물 | 5-Bromo-2-chloropyrimidine | HCID 606665 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 5-Bromo-N-sec-butylpyrimidin-2-amine | HCID 63873787 | — |
반응 단계
In a sealed tube 2.00 g (10.3 mmol) 5-bromo-2-chloropyrimidine and 3.13 mL (31.0 mmol) sec-butylamin are added to 12 mL ACN. The reaction mixture is stirred at 120° C. for 2 h, then diluted with EtOAc and washed with water (2×). The org. phase is dried with MgSO4 and the solvent is removed in vacuo. C8H12BrN3 (M=230.1 g/mol)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08530460B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_09 |
|---|
| ORD ID | ord-1d99d59c38ef44dfa691cbcecf9f42e2 |
|---|
| 출처 메모 | uspto-grants-2013_09 |
|---|
