Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Quinolinecarboxaldehyde → 4-Quinolin-2-ylmethyl-piperazine-1-carboxylic acid (4-fluoro-phenyl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Quinolinecarboxaldehyde | HCID 79619 | — |
| 반응물 | N-(4-Fluorophenyl)piperazine-1-carboxamide | HCID 16228149 | — |
| 생성물 | 4-Quinolin-2-ylmethyl-piperazine-1-carboxylic acid (4-fluoro-phenyl)-amide | HCID 11710321 | — |
반응 단계
The title compound was prepared from piperazine-1-carboxylic acid (4-fluoro-phenyl)-amide and 2-quinolinecarbaldehyde. 1H NMR (400 MHz, CDCl3): 8.16 (d, J=8.3 Hz, 1H), 8.08 (d, J=8.6 Hz, 1H), 7.82 (d, J=7.6 Hz, 1H), 7.74-6.69 (m, 1H), 7.63 (d, J=8.3 Hz, 1H), 7.56-7.52 (m, 1H), 7.32-7.25 (m, 2H), 6.99-6.94 (m, 2H), 6.38 (s, 1H), 3.88 (s, 2H), 3.52 (t, J=5.1 Hz, 4H), 2.60 (t, J=5.1 Hz, 4H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08530476B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-5e2e44c9a19c4447baf14d54b04afb40 |
| 출처 메모 | uspto-grants-2013_09 |