Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenyl pyridin-3-ylcarbamate → 4-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethyl)-piperazine-1-carboxylic acid pyridin-3-ylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenyl pyridin-3-ylcarbamate | HCID 6935890 | — |
| 반응물 | Difluoromethylenedioxybenzylpiperazine | HCID 66553702 | — |
| 생성물 | 4-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethyl)-piperazine-1-carboxylic acid pyridin-3-ylamide | HCID 57880883 | — |
반응 단계
The title compound was prepared from pyridin-3-yl-carbamic acid phenyl ester and 1-(2,2-difluoro-benzo[1,3]dioxol-5-ylmethyl)-piperazine in analogy with Example 142. 1H NMR (400 MHz, CDCl3): 8.46 (d, J=2.5 Hz, 1H), 8.23-8.21 (m, 1H), 7.99-7.96 (m, 1H), 7.22-7.19 (m, 2H), 7.11 (s, 1H), 6.99-6.98 (m, 2H), 3.54-3.52 (m, 4H), 3.49 (s, 2H), 2.46-2.44 (m, 4H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08530476B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-441e133eb6fc4fe0ab56a5c78bfca2f0 |
| 출처 메모 | uspto-grants-2013_09 |