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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 407088생성일: 2026년 10월 26일

(S)-(+)-Tetrahydrofurfurylamine → US10213427, Example 100

https://huagongshe.com/reaction/407088

반응식

참여 물질

역할이름HCID투입량
반응물(S)-(+)-TetrahydrofurfurylamineHCID 641530—
반응물2-(4-{3-[3-({[(2,2,2-Trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}phenyl)propanoic acidHCID 67980157—
생성물US10213427, Example 100HCID 57386930—

반응 단계

This compound was prepared by using procedure analogous to those described for the synthesis of Example 98, Step 9 starting from 2-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}phenyl)propanoic acid and 1-[(25)-tetrahydrofuran-2-yl]methanamine. LCMS (M+H)+: m/z=567.3

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08754114B2
출처 데이터셋uspto-grants-2014_06
ORD IDord-0a413573f2d449a0b0b513fbe09f877a
출처 메모uspto-grants-2014_06