1-(3-Chloropropyl)-pyrrolidine → 4-Azoniaspiro[3,4]octane chloride

HRID 407278노트

반응식

HRID 407278 반응식
[Cl:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:9][CH2:8][CH2:7][CH2:6]1>O>[Cl-:1].[CH2:2]1[N+:5]2([CH2:9][CH2:8][CH2:7][CH2:6]2)[CH2:4][CH2:3]1

참가 물질

3

반응물 1

HCID 113210281-(3-Chloropropyl)-pyrrolidine

생성물 1

HCID 674420294-Azoniaspiro[3,4]octane chloride

시약·촉매·용매 1

HCID 962Water용매2회

반응 조건

온도
20 °C

실험 절차

An aqueous solution of 4-azoniaspiro[3,4]octane chloride was prepared by adding 1-(3-Chloropropyl)pyrrolidine (128 ml) to water (100 ml) at 94° C. over 25 minutes. The mixture was stirred for a further 5 minutes to give a clear yellow solution. This was cooled to 20° C. and stored in a bottle. Line washes of water (2×25 ml) were applied.

후처리

  1. customto give a clear yellow solution

출처 및 근거

ORD 기록
ord-472bb1f6e5ae4ec6874eeba1ff218b05
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08754240B2

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