2-Isopropylpyridine → 1-Oxo-2-(propan-2-yl)-1lambda~5~-pyridine
반응식
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)([CH3:3])[CH3:2].C1C=C(Cl)C=C(C(OO)=[O:18])C=1>C(Cl)Cl>[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N+:5]=1[O-:18])([CH3:3])[CH3:2]참가 물질
4
실험 절차
A mixture of isopropylpyridine (2.1 g, 17.75 mmol) and m-CPBA (5.0 g, 1.3 eq.) in CH2Cl2 was stirred overnight at room temperature. Then, the reaction mixture was diluted with CH2Cl2 (twice the volume) and successively washed with aqueous sodium bicarbonate (twice) and brine, dried (Na2SO4) and evaporated to give 2.0 g (85%) of the title compound 104.
후처리
- washsuccessively washed with aqueous sodium bicarbonate (twice) and brine
- dry with materialdried (Na2SO4)
- customevaporated
출처 및 근거
- ORD 기록
- ord-3b5a2279c0dd4dc4be59883f719edeea
- 출처 데이터셋
- uspto-grants-2014_06
- 특허 번호
- US08754106B2
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