2-Isopropylpyridine → 1-Oxo-2-(propan-2-yl)-1lambda~5~-pyridine

HRID 407569

반응식

HRID 407569 반응식
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1)([CH3:3])[CH3:2].C1C=C(Cl)C=C(C(OO)=[O:18])C=1>C(Cl)Cl>[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N+:5]=1[O-:18])([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 695232-IsopropylpyridineHCID 70297m-Chloroperbenzoic acid

생성물 1

HCID 131720791-Oxo-2-(propan-2-yl)-1lambda~5~-pyridine수율 85%

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

A mixture of isopropylpyridine (2.1 g, 17.75 mmol) and m-CPBA (5.0 g, 1.3 eq.) in CH2Cl2 was stirred overnight at room temperature. Then, the reaction mixture was diluted with CH2Cl2 (twice the volume) and successively washed with aqueous sodium bicarbonate (twice) and brine, dried (Na2SO4) and evaporated to give 2.0 g (85%) of the title compound 104.

후처리

  1. washsuccessively washed with aqueous sodium bicarbonate (twice) and brine
  2. dry with materialdried (Na2SO4)
  3. customevaporated

출처 및 근거

ORD 기록
ord-3b5a2279c0dd4dc4be59883f719edeea
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08754106B2

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