Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 2-Phthalimidoethanesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2-Phthalimidoethanesulfonyl chloride | HCID 308739 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 2-Phthalimidoethanesulfonamide | HCID 96092 | — |
반응 단계
2-Phthalimidoethanesulfonyl chloride (2.0 g) was added portion wise to a solution of 0.5 M of ammonia in dioxane (15 ml) and the solution obtained this way was stirred at room temperature. After 48 hours the reaction mixture was poured in water (50 ml) causing the title compound to precipitate. The product was collected by filtration. Yield: 1.52 g (83%) of a solid. 1H-NMR (DMSO-δ6) δ (ppm) 7.92-713 (m, 4H), 7.06 (s, 2H), 6.88-3.93 (m, 2H), 3.37-3.30 (m, 2H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08530486B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-01d3b421636a46c9afeff37871c6b667 |
| 출처 메모 | uspto-grants-2013_09 |