Ammonia → 2-Phthalimidoethanesulfonamide

HRID 40757

반응식

HRID 40757 반응식
[C:1]1(=[O:17])[N:5]([CH2:6][CH2:7][S:8](Cl)(=[O:10])=[O:9])[C:4](=[O:12])[C:3]2=[CH:13][CH:14]=[CH:15][CH:16]=[C:2]12.[NH3:18]>O1CCOCC1.O>[C:1]1(=[O:17])[N:5]([CH2:6][CH2:7][S:8]([NH2:18])(=[O:10])=[O:9])[C:4](=[O:12])[C:3]2=[CH:13][CH:14]=[CH:15][CH:16]=[C:2]12

참가 물질

5

반응물 2

HCID 222AmmoniaHCID 3087392-Phthalimidoethanesulfonyl chloride

생성물 1

HCID 960922-Phthalimidoethanesulfonamide

시약·촉매·용매 2

HCID 962Water용매HCID 312751,4-Dioxane용매

실험 절차

2-Phthalimidoethanesulfonyl chloride (2.0 g) was added portion wise to a solution of 0.5 M of ammonia in dioxane (15 ml) and the solution obtained this way was stirred at room temperature. After 48 hours the reaction mixture was poured in water (50 ml) causing the title compound to precipitate. The product was collected by filtration. Yield: 1.52 g (83%) of a solid. 1H-NMR (DMSO-δ6) δ (ppm) 7.92-713 (m, 4H), 7.06 (s, 2H), 6.88-3.93 (m, 2H), 3.37-3.30 (m, 2H).

후처리

  1. customthe solution obtained this way

출처 및 근거

ORD 기록
ord-01d3b421636a46c9afeff37871c6b667
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08530486B2

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