Methylamine → HCID 178462848, 화합물

HRID 40761

반응식

HRID 40761 반응식
[C:1]1(=[O:17])[N:5]([CH2:6][CH2:7][S:8](Cl)(=[O:10])=[O:9])[C:4](=[O:12])[C:3]2=[CH:13][CH:14]=[CH:15][CH:16]=[C:2]12.[CH3:18][NH2:19]>C1COCC1.O>[C:4]1(=[O:12])[N:5]([CH2:6][CH3:7])[C:1](=[O:17])[C:2]2=[CH:16][CH:15]=[CH:14][CH:13]=[C:3]12.[CH3:18][NH:19][SH:8](=[O:9])=[O:10]

참가 물질

5

반응물 2

HCID 6329MethylamineHCID 3087392-Phthalimidoethanesulfonyl chloride

생성물 1

HCID 178462848HCID 178462848, 화합물

시약·촉매·용매 2

HCID 962Water용매HCID 8028Tetrahydrofuran용매

실험 절차

2-Phthalimidoethanesulfonyl chloride (2.0 g) was added portion wise to a solution of 2.0 M methylamine in THF (15 ml) and the solution obtained this way was stirred at room temperature. After 48 hours the reaction mixture was poured in water (50 ml) causing the title compound to precipitate. The product was collected by filtration and recrystallized from EtOH:water, 50:1 to yield: 1.04 g (48%) of the desired product as a solid.

후처리

  1. customthe solution obtained this way

출처 및 근거

ORD 기록
ord-15af8745e0104771a2b59e6f0ad73bcc
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08530486B2

연결된 노트

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