참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 2,2-Dimethyl-4-butyrolactone | HCID 94746 | — |
| 촉매 | Phenolphthalein | HCID 4764 | — |
| 용매 | Water ethanol | HCID 19096565 | — |
| 생성물 | Potassium 4-hydroxy-2,2-dimethylbutyrate | HCID 23712640 | 71.1% |
반응 단계
A mixture of dihydro-3,3-dimethyl-2(3H)-furanone (10 mmol; 1.14 g), aqueous 1 M KOH solution (10 mmol) and one drop of phenolphthalein indicator (0.5% w/v in EtOH/water (1:1)) is stirred at 105° C. for 3.5 hours. The mixture is cooled to ambient temperature and concentration under reduced pressure. To the residue is added 10 mL of EtOH. To the solution is added 50 ml of Et2O, and the solid isolated by filtration and dried under 100 mbar at 50° C. to give potassium 4-hydroxy-2,2-dimethylbutyrate (1.21 g, 71%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08759365B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_06 |
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| ORD ID | ord-35ae9b314b1645268a359b196c797298 |
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| 출처 메모 | uspto-grants-2014_06 |
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