Methanol → HCID 66895058, 화합물

HRID 409613노트

반응식

HRID 409613 반응식
[CH3:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]1C=O.[CH:13]1([NH2:23])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15][CH2:14]1.[CH3:24]O>>[CH3:1][CH:2]1[CH2:10][C:9]2[C:4](=[C:5]([CH:24]=[N:23][CH:13]3[C:22]4[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=4)[CH2:16][CH2:15][CH2:14]3)[CH:6]=[CH:7][CH:8]=2)[NH:3]1

참가 물질

4

반응물 3

HCID 887MethanolHCID 180661,2,3,4-Tetrahydro-1-naphthylamineHCID 127981582-Methyl-2,3-dihydro-1H-indole-1-carbaldehyde

생성물 1

HCID 66895058HCID 66895058, 화합물

실험 절차

1.68 g of 2-methylindolino aldehyde was dissolved in 35 ml of methanol and then 1.58 ml of 1,2,3,4-tetrahydro naphthyl amine was slowly added thereto. The mixture was stirred at room temperature overnight before some precipitates were slowly formed, and then was filtered while being washed with methanol to provide ivory solids as a clean product (2.3 g). (Yield: 75%) This compound was a mixture of two stereoisomers at a ratio of 1:0.6.

후처리

  1. customwere slowly formed
  2. filtrationwas filtered
  3. washwhile being washed with methanol

출처 및 근거

ORD 기록
ord-f6f7a432e2e34bf48f7216466847115b
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759461B2

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