Trifluoroacetic acid → 2-(4-Piperidin-4-yl-phenyl)-propionic acid methyl ester
반응식
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[CH:19]=[CH:18][C:17]([CH:20]([C:22]([O:24][CH3:25])=[O:23])[CH3:21])=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.C(O)(C(F)(F)F)=O>C(Cl)Cl>[CH3:25][O:24][C:22](=[O:23])[CH:20]([C:17]1[CH:18]=[CH:19][C:14]([CH:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)=[CH:15][CH:16]=1)[CH3:21]참가 물질
4
실험 절차
The compound is prepared analogously to Example XI.1 using 4-[4-(1-methoxycarbonyl-ethyl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester (VIII.1) as educt and TFA in DCM instead of HCl.
출처 및 근거
- ORD 기록
- ord-47f5e500d2944eca8497ba0406725038
- 출처 데이터셋
- uspto-grants-2014_06
- 특허 번호
- US08759528B2
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