Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine → Isoquinoline-3-carbohydrazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine | HCID 9321 | — |
| 반응물 | Methyl 3-isoquinolinecarboxylate | HCID 725374 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Isoquinoline-3-carbohydrazide | HCID 55263898 | 86% |
반응 단계
To a solution of methyl isoquinoline-3-carboxylate (10 g, 53.42 mmol) in ethanol (100 mL) was added hydrazine (17.1 g). The reaction mixture was refluxed for 30 min and concentrated under high vacuum to remove hydrazine. The resulting residue was triturated with ethanol (20 mL) to give isoquinoline-3-carbohydrazide (8.6 g, 86%). LRMS (M+H+) m/z 188.1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08759374B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-4011f0480f4e446aa3625771427965f9 |
| 출처 메모 | uspto-grants-2014_06 |