HCID 17925871, 화합물 → 4-CarboxyMethyl-cyclohexanecarboxylic acid ethyl ester

HRID 410030노트

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HRID 410030 반응식
[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][C:9](=[CH:12][C:13]([OH:15])=[O:14])[CH2:8][CH2:7]1)=[O:5])[CH3:2]>CCO.[Pd]>[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][CH:9]([CH2:12][C:13]([OH:15])=[O:14])[CH2:8][CH2:7]1)=[O:5])[CH3:2]

참가 물질

4

반응물 1

HCID 17925871HCID 17925871, 화합물

생성물 1

HCID 158961924-CarboxyMethyl-cyclohexanecarboxylic acid ethyl ester수율 42%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution of 2-(4-(ethoxycarbonyl)cyclohexylidene)acetic acid (6.0 g, 28.3 mmol) in EtOH (50 ml) was slowly added 10% Pd/C (306 mg). The solution was hydrogenated overnight. The catalyst was filtered off. The filtrate was concentrated in vacuo to afford 2.5 g of product as colorless oil (42%).

후처리

  1. filtrationThe catalyst was filtered off
  2. concentrationThe filtrate was concentrated in vacuo

출처 및 근거

ORD 기록
ord-884459c38d28486abf5c93ec89e88205
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759548B2

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