2-(2,2-Difluoro-ethoxy)-4-amino-5-nitro-benzoic acid → 2-(2,2-Difluoro-ethoxy)-4,5-diamino-benzoic acid

HRID 410093노트

반응식

HRID 410093 반응식
[F:1][CH:2]([F:18])[CH2:3][O:4][C:5]1[CH:13]=[C:12]([NH2:14])[C:11]([N+:15]([O-])=O)=[CH:10][C:6]=1[C:7]([OH:9])=[O:8]>[Pd]>[F:1][CH:2]([F:18])[CH2:3][O:4][C:5]1[CH:13]=[C:12]([NH2:14])[C:11]([NH2:15])=[CH:10][C:6]=1[C:7]([OH:9])=[O:8]

참가 물질

3

반응물 1

HCID 871396792-(2,2-Difluoro-ethoxy)-4-amino-5-nitro-benzoic acid

생성물 1

HCID 871397232-(2,2-Difluoro-ethoxy)-4,5-diamino-benzoic acid수율 99%

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

The subtitle compound is prepared from 2-(2,2-difluoro-ethoxy)-4-amino-5-nitro-benzoic acid (example 2c) with Pd/C and H2 in analogy to example 1f.

출처 및 근거

ORD 기록
ord-1e353d3f3c6d43faa5000cb6fdac6d6d
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759537B2

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