Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Fluoroindole → Sodium 6-Fluoro-1H-indole-2-sulfonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Fluoroindole | HCID 351278 | — |
| 반응물 | Sodium Bisulfite | HCID 23665763 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Sodium 6-Fluoro-1H-indole-2-sulfonate | HCID 86634332 | 29.5% |
반응 단계
To a solution of 23.4 g sodium bisulfite in 80 ml water a solution of 13.5 g 6-fluoro indole in ethanol is added drop wise. The obtained suspension is stirred at room temperature over night. The precipitate is filtered and washed with cold water, cold methanol and diethyl ether. 7.0 g (29%) of the title compound are obtained as a colourless solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08530493B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-524347121123467c90bcf38b3fc5d8c2 |
| 출처 메모 | uspto-grants-2013_09 |