Methylamine → 4-(Methylamino)-3-nitrobenzoic acid

HRID 410716

반응식

HRID 410716 반응식
F[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[CH3:14][NH2:15]>C1COCC1>[CH3:14][NH:15][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12]

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 679874-Fluoro-3-nitrobenzoic acid

생성물 1

HCID 2834754-(Methylamino)-3-nitrobenzoic acid

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

4-Methylamino-3-nitro-benzoic acid (825 mg) was prepared by following General Procedure A starting from 4-fluoro-3-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 8.1 mL) in THF. The crude product was used in the next step without further purification.

후처리

  1. customThe crude product was used in the next step without further purification

출처 및 근거

ORD 기록
ord-705eeba1d51b4124a7575f0951cb9830
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759535B2

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