Methylamine → 3-(Methylamino)-4-nitrobenzoic acid

HRID 410757노트

반응식

HRID 410757 반응식
Cl[C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6].[CH3:14][NH2:15]>C1COCC1>[CH3:14][NH:15][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6]

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 5209533-Chloro-4-nitrobenzoic acid

생성물 1

HCID 221846233-(Methylamino)-4-nitrobenzoic acid

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

3-Methylamino-4-nitro-benzoic acid (1.1 g) was prepared by following General Procedure A starting from 3-chloro-4-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 8.1 mL) in THF. The crude product was used in the next step without further purification.

후처리

  1. customThe crude product was used in the next step without further purification

출처 및 근거

ORD 기록
ord-f69696e8839d43f3a39a54262b77c284
출처 데이터셋
uspto-grants-2014_06
특허 번호
US08759535B2

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