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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 411054생성일: 2026년 10월 27일

1,2-Dichloroethane → 2-(6-Ethoxy-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid dimethylcarbamoylmethyl-amide

https://huagongshe.com/reaction/411054

반응식

참여 물질

역할이름HCID투입량
반응물1,2-DichloroethaneHCID 11—
반응물Amino-6-ethoxybenzothiazole, 2-HCID 7192—
반응물3-Amino-N-dimethylcarbamoylmethyl-4-methylamino-benzamideHCID 67333499—
용매DimethylformamideHCID 6228—
생성물2-(6-Ethoxy-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid dimethylcarbamoylmethyl-amideHCID 866569706.4%

반응 단계

2-(6-Ethoxy-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid dimethylcarbamoylmethyl-amide (15 mg) was prepared by following General Procedure D starting from 6-ethoxy-benzothiazol-2-ylamine (100 mg), 3-amino-N-dimethylcarbamoylmethyl-4-methylamino-benzamide (150 mg), thioCDI (150 mg) and EDC (150 mg) in DMF (3 mL). LC/MS: m/z 452.6.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08759535B2
출처 데이터셋uspto-grants-2014_06
ORD IDord-751121ddd7874a63be61626dd0990e5e
출처 메모uspto-grants-2014_06