Benzeneacetic acid, 4-bromo- → 2-[(4-Bromophenyl)acetamido]butyric acid isobutyl ester

HRID 411477

반응식

HRID 411477 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=1)[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

참가 물질

3

반응물 2

HCID 74654Benzeneacetic acid, 4-bromo-HCID 13743360Isobutyl 2-aminobutyrate

생성물 1

HCID 155476402-[(4-Bromophenyl)acetamido]butyric acid isobutyl ester

실험 절차

Following General Procedure BI above and using 4-bromophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

후처리

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

출처 및 근거

ORD 기록
ord-c00a5d7d258a44719473b69041dae049
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06559141B2

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