Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorotrimethylsilane → Methyl 2,2,4-Trimethyl-3-silyloxypent-3-enecarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorotrimethylsilane | HCID 6397 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 2,2,4,4-Tetramethyl-1,3-cyclobutanedione | HCID 13617 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 생성물 | Methyl 2,2,4-Trimethyl-3-silyloxypent-3-enecarboxylate | HCID 123759875 | — |
반응 단계
84 g (0.6 mol) of 2,2,4,4-tetramethylcyclobutane-1,3-dione and 32.4 g (0.6 mol) of sodium methylate were mixed together in 320 ml of tetrahydrofuran. 65.1 g (0.6 mol) of trimethylsilyl chloride were added dropwise and the mixture was stirred. The reaction mixture was then concentrated and the residue was taken up with diethyl ether. The solid was filtered off with suction and the mother liquor was concentrated. Yield: 135 g (89%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06559343B1 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-018233e2db2a44b78cd771c96c80a5be |
| 출처 메모 | uspto-grants-2003_05 |