Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isopropanol → N4-Phenylquinazoline-4,6-diamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 6-Nitro-N-phenylquinazolin-4-amine | HCID 5328189 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Water ethanol | HCID 19096565 | — |
| 생성물 | N4-Phenylquinazoline-4,6-diamine | HCID 5328187 | — |
반응 단계
A solution of 4-(phenylamino)-6-nitroquinazoline in ethanol/water and a polar solvent such as iso-propylalcohol is reacted at reflux temperature with hydrazine hydrate and Raney®Nickel. The reaction mixture is filtered, evaporated and purified by silica gel chromatography, to give the product, 4-(phenylamino)-6-aminoquinazoline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06562319B2 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-ce5fada03a2a41768303a391ff3f672c |
| 출처 메모 | uspto-grants-2003_05 |