(+-)-Homocysteine → Captopril

HRID 411951

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HRID 411951 반응식
N[C@@H](CCC(N[C@H:11]([C:14]([NH:16][CH2:17][C:18]([OH:20])=[O:19])=[O:15])[CH2:12][SH:13])=O)C(O)=O.N[C@H:22]([C:25](O)=O)[CH2:23]S.N[CH:29](C(O)=O)CCS.CN(C1C=CC2N=C3C(=CC(C=C3)=[N+](C)C)SC=2C=1)C.C(N[C@H](C(O)=O)CS)(=O)C>>[CH3:29][C@@H:11]([C:14]([N:16]1[C@H:17]([C:18]([OH:20])=[O:19])[CH2:25][CH2:22][CH2:23]1)=[O:15])[CH2:12][SH:13]

참가 물질

6

실험 절차

Glutathione, L-cysteine, DL-homocysteine, D-penicillin, hemoglobin (bovine), methylene blue and Medium 199 sets were purchased from Sigma Chemical Co., St. Louis, Mo. N-acetylcysteine was obtained from Aldrich Chemical Co., Milwaukee, Wis. Captopril was kindly provided by Dr. Victor Dzau. Sodium nitrite, histamine and methacholine were purchased from Fisher Scientific, Fairlawn, N.J. Leukotriene D4 was purchased from Anaquest, BOC Inc., Madison, Wis. Antibiotic/antimycotic mixture (10,000 U/ml penicillin G sodium, 10,000 mg/ml, streptomycin sulfate, 25 mg/ml amphotericin B) was purchased from Gibco laboratories, Grand Island, N.Y. Radioimmunoassay kits for the determination of cyclic GMP were purchased from New England Nuclear, Boston, Mass.

출처 및 근거

ORD 기록
ord-85a3f89982fb48c6b69ddd79a9eec375
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06562344B1

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