Potassium Carbonate → 18-Crown-6

HRID 412063노트

반응식

HRID 412063 반응식
[CH3:1][O:2][C:3]1[CH:15]=CC=CC=1CN1CCNCC1.[C:16](=[O:19])([O-])[O-].[K+].[K+]>CN(C=O)C>[CH2:1]1[O:2][CH2:3][CH2:15][O:19][CH2:16][CH2:1][O:2][CH2:3][CH2:15][O:19][CH2:16][CH2:1][O:2][CH2:3][CH2:15][O:19][CH2:16]1

참가 물질

4

반응물 2

HCID 11430Potassium CarbonateHCID 5781921-(2-Methoxybenzyl)piperazine

생성물 1

HCID 2855718-Crown-6

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

3.0 g of intermediate compound 8a were reacted in 70 ml of DMF with 2.9 g of N-(2-methoxybenzyl)piperazine analogously to Example 8b in the presence of 5.7 g of potassium carbonate and a spatula tipful of 18-crown-6, 1.3 g (27%) of the product being obtained.

출처 및 근거

ORD 기록
ord-df73b472d38549b88c863505e8777eea
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06562827B1

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